McMaster University

McMaster University

Faculty

Cecile Fradin

Cecile Fradin, PhD

Joint Member
Biochemistry and Biomedical Sciences

Associate Professor, Physics and Astronomy

346 A.N. Bourns Science Building
McMaster University
905-525-9140 ext. 23181

fradin@physics.mcmaster.ca

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Research

  • Molecular Biophysics

I am interested in studying the dynamics of single molecules inside biological systems using optical tools. Dynamics is essential to the survival of the cell, which is a biological unit in permanent evolution, and which has to be able to process and react to information. Dynamical processes inside the cell happen on a very wide range of length and time-scales, and are governed by complex and intricate rules and mechanisms. At the scale of the molecule, they are of interest for the physicist as well as for the biologist, since they involve basic transformation of chemical or thermal energy into mechanical energy. In order to unravel their exact mechanisms, in vivo quantitative measurements at the single molecule level are required, which recent developments in the domain of fluorescence techniques, single molecule detection, and recombinant protein technology now offers the possibility to do.

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