Professor - Part Time
Biochemistry and Biomedical Sciences
Department of Anatomy and Cell Biology, McGill University
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- Electron Microscopy Studies of the HtrA family of Proteases
Most important biological processes in bacteria are not done by an individual
protein but for multicomponent systems comprised of several proteins.
Furthermore, these assemblies are like dynamic machines continuously changing
conformations and sometimes also subunit composition. In our lab, we use
cryo-electron microscopy combined with molecular biology and biochemistry
analysis to characterize the assembly and mechanisms of these macromolecular
machines. Ortega lab members work on research projects aiming to understand how
the bacterial ribosome is assembled and how important bacterial proteases function.