Health Research Methods, Evidence, and Impact

Jason Busse

BSc (University of Toronto), MSc (University of Toronto), DC (CMCC), PhD (McMaster)

Associate Professor, Department of Anesthesia

Joint Member, Department of Health Research Methods, Evidence, and Impact

Canadian Institute of Health Research New Investigator Award (2009-2013)

Member, CLARITY (Clinical Advances through Research and Information Translation)

905.525.9140 x21731

McMaster University
1200 Main St. West
Hamilton, ON, L8S 4K1

Academic Interests

Dr. Busse’s clinical interests include insurance medicine, orthopedic trauma, chronic pain and other medically unexplained syndromes, and management of complex disability. He is the Co-Principal Investigator of the TRUST trial, a multi-centre, randomized controlled trial of low-intensity, pulsed ultrasound bone-stimulation in patients undergoing intramedullary nailing for tibial fracture. Dr. Busse is also interested in methodological research including, for example, expertise-based randomization and the use of composite endpoints in clinical trials.

Selected Publications

  1. Ferreira-González I, Busse JW, Heels-Ansdell D, et al. Problems with use of composite end points in cardiovascular trials: systematic review of randomised controlled trials. BMJ. 2007; 334: 786-792
  2. Johnston BC, da Costa BR, Devereaux PJ, Akl EA, Busse JW; Expertise-Based RCT Working Group. The Use of Expertise Based Randomized Controlled Trials to Assess Spinal Manipulation and Acupuncture for Low Back Pain: A Systematic Review. Spine. 2008; 33: 914-918
  3. Busse JW, Montori VM, Krasnik C, Patelis-Siotis I, Guyatt GH, for the Medically Unexplained Syndromes Research Group. Psychological Intervention for Premenstrual Syndrome: A Meta-Analysis of Randomized Controlled Trials. Psychother Psychosom. 2009; 78: 6-15.
  4. Busse JW, Kaur J, Mollon B, Bhandari M, Tornetta P 3rd, Schünemann HJ, Guyatt GH. Low intensity pulsed ultrasonography for fractures: systematic review of randomised controlled trials. BMJ. 2009; 338: b351.
  5. Busse JW, Guyatt GH. Optimizing the use of patient data to improve outcomes for patients: narcotics for chronic noncancer pain. Expert Rev Pharmacoecon Outcomes Res. 2009; 9: 171-9.
  6. Busse JW, Obremskey WT. Principles of Designing an Orthopaedic Case-Control Study. J Bone Joint Surg (Am). 2009; 91: 15-20.
  7. Busse JW, Bhandari M, Guyatt GH, et al. Use of both short musculoskeletal function assessment questionnaire and short form-36 among tibial-fracture patients was redundant. J Clin Epidemiol. 2009; 62(11): 1210-1217.
  8. Kulkarni AV, Aziz B, Shams I, Busse JW. Comparisons of Citations in Web of Science, Scopus, and Google Scholar for Articles Published in General Medical Journals. JAMA. 2009; 302(10): 1092-1096.
  9. Busse JW, Jacobs C, Ngo T, Rodine R, Torrance D, Jim J, Kulkarni AV, Petrisor B, Drew B, Bhandari M. Attitudes Toward Chiropractic: A Survey of North American Orthopedic Surgeons. Spine (Phila Pa 1976). 2009; 34(25): 2818-2825.
  10. Sun X, Briel M, Busse JW, You JJ, Akl EA, Mejza F, Bala M, Bassler D, Mertz D, Diaz-Granados N, Vandvik PO, Malaga G, Srinathan SK, Dahm P, Johnston BC, Alonso-Coello P, Hassouneh B,  Walter SD, Heels-Ansdell DM, Altman DG, Guyatt GH. Study characteristics associated with reporting of subgroup analyses in randomized controlled trials. BMJ. 2011; 342: d1569.

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