Health Research Methods, Evidence, and Impact

Shanil Ebrahim

BSc, MSc, MSc, PhD

Assistant Professor (part-time), Department of Health Research Methods, Evidence, and Impact

Meta Research Innovation Center at Stanford, Stanford University

McMaster University
Department of Anesthesia
1200 Main St. West, Room 2112 
Hamilton, ON, L8S 4K1


Academic Interests

Dr. Ebrahim's research interests include big data analytics, predictive modeling, comparative effectiveness analyses, meta-analytic methods, insurance medicine, disability management, mental health issues in the workplace, and chronic pain. His primary focus is in determining optimal management and evaluating predictors of recovery and long-term patient important outcomes in chronic health disorders. Dr. Ebrahim's primary methodological focus is in improving the accuracy and application of predictive modeling, assessing the impact of missing participant data in randomized trials and meta-analyses, and improving interpretability amongst clinicians and decision-makers. 

Selected Publications

  1. Ebrahim S, Sohani ZN, Montoya L, Agarwal A, Thorlund K, Mills EJ, Ioannidis JP. Reanalyses of randomized clinical trial data. JAMA. 2014; 312(10):1024-1032.
  2. Ebrahim S, Malachowski C, Kamal El Din M, Mulla SM, Montoya L, Bance S, Busse JW. Measures of patients' expectations about recovery: a systematic review. J Occup Rehabil. 2015;25(1):240-55.
  3. Ebrahim S, Sava H, Kunz R, Busse JW. Ethics and legalities associated with independent medical evaluations. CMAJ. 2014 Feb 3.
  4. Kasenda B, von Elm E, You J, Blümle A, Tomonaga Y, Saccilotto R, Amstutz A, Bengough T, Meerpohl JJ, Stegert M, Tikkinen KA, Neumann I, Carrasco-Labra A, Faulhaber M, Mulla SM, Mertz D, Akl EA, Bassler D, Busse JW, Ferreira-González I, Lamontagne F, Nordmann A, Gloy V, Raatz H, Moja L, Rosenthal R, Ebrahim S, Schandelmaier S, Xin S, Vandvik PO, Johnston BC, Walter MA, Burnand B, Schwenkglenks M, Hemkens LG, Bucher HC, Guyatt GH, Briel M. Prevalence, characteristics, and publication of discontinued randomized trials. JAMA. 2014;311(10):1045-51.
  5. Ebrahim S, Guyatt GH, Walter SD, Heels-Ansdell D, Bellman M, Hanna SE, Patelis-Siotis I, Busse JW. Association of psychotherapy with disability benefit claim closure among patients disabled due to depression. PLoS One. 2013 Jun 28;8(6):e67162.
  6. Ebrahim S, Montoya L, Truong W, Hsu S, Kamal El Din M, Carrasco-Labra A, Busse JW, Walter SD, Heels-Ansdell D, Couban R, Patelis-Siotis I, Bellman M, de Graaf LE, Dozois DJ, Bieling PJ, Guyatt GH. Effectiveness of Cognitive Behavioral Therapy for Depression in Patients Receiving Disability Benefits: A Systematic Review and Individual Patient Data Meta-Analysis. PLoS One. 2012; 7 (11):e50202
  7. Ebrahim S, Akl EA, Mustafa RA, Sun X, Walter SD, Heels-Ansdell D, Alonso-Coello P, Johnston BC, Guyatt GH.Addressing continuous data for participants excluded from trial analysis: a guide for systematic reviewers. J Clin Epidemiol. 2013 Sep;66(9):1014-1021
  8. Akl EA, Johnston BC, Alonso-Coello P, Neumann I, Ebrahim S, Briel M, Cook DJ, Guyatt GH. Addressing dichotomous data for participants excluded from trial analysis: a guide for systematic reviewers. PLoS One. 2013;8(2):e57132.
  9. Ebrahim S, Busse JW, Guyatt GH, Birch S. Managing moral hazard in motor vehicle accident insurance claims. J Public Health Policy. 2013 May;34(2):320-9.
  10. Schandelmaier S, Ebrahim S, Burkhardt SC, de Boer WE, Zumbrunn T, Guyatt GH, Busse JW, Kunz R. Return to work coordination programmes for work disability: a meta-analysis of randomised controlled trials. PLoS One. 2012;7(11):e49760

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