Health Research Methods, Evidence, and Impact

Charlie Goldsmith

BSc. (Manitoba), MSc. (Manitoba),
PhD (North Carolina State)

Professor Emeritus, Department of Health Research Methods, Evidence, and Impact

905.522.1155 x 34903

Biostatistics Unit/FSORC
3rd Floor Martha, Room H322
St. Joseph's Healthcare Hamilton
50 Charlton Avenue East
Hamilton, ON
L8N 4A6

Administrative Assistant: Rosemary Oliveira
905-522-1155 x 34905


After completing his PhD at North Carolina State University, Raleigh, in Experimental Design, a sub-area of Statistics, in 1969 Dr. Goldsmith returned to Canada to take up a post at McMaster University. He has spent his entire career at McMaster apart from sabbaticals and leaves at other locations.

Charlie is a Fellow of The American Statistical Association and in 1995 won a Founders Award from The American Statistical Association. He is an elected member of the International Statistical Institute. He is currently a member of the Editorial Board of The Journal of Rheumatology, Pharmacoepidemiology and Drug Safety, The Palmer Journal of Research, and the Canadian Journal of Chiropractic, BMC-Trials and the Journal of Bodywork & Movement Therapies. He has served on a variety provincial, national and international grant review bodies.

Dr. Goldsmith's research interests are in Statistical Methodology related to the evaluation of therapies involved in musculo-skeletal conditions, namely, rheumatology, physical therapy, chiropractic, etc, and more recently in surgery; developing research methodology for carrying out studies of quality-of-life in patients who use pharmaceutical agents; developing standards for research quality assessment in manuscripts, grants and research articles, developing improved understanding of graphical communication, and helping health care delivery adopt quality improvement methods.

Recent Graduate Students
Marek Smieja (PhD)
Pauline Boulos (MSc)

Selected Publications

  1. Hansebout RR, Cornacchi SD, Haines AT, Goldsmith CH: Users’ guide to the surgical literature: How to use an article about prognosis.  Can J Surg 2009;52(4):328-336.
  2. Vernon HT, Jansz G, Goldsmith CH, McDermaid C: A Randomized, Placebo Controlled Clinical Trial of Chiropractic and Medical Prophylactic Treatment
    of Adults with Tension-Type Headache: Results from a Stopped Trial.  J Manipulative Physiol Ther 2009;32:344-351.
  3. MacDermid JC, Walton DM, Avery S, Blanchard A, Etruw E, McAlpine C, Goldsmith CH: Measurement Properties of the Neck Disability Index: A Systematic Review.  J Orthop Sports Phys Ther 2009;39(5):400-417.  DOI: 10.2519/jospt.2009.2930
  4. Gross AR, Haines AT, Goldsmith CH, Santiguida L, McLaughlin LM, Peloso PMJ, Burnie S, Hoving J for the Cervival Overview Group (COG): Knowledge to Action: A Challenge for Neck Pain Treatment.  J Orthop Sports Phys Ther 2009;39(5):351-363.  DOI: 10.2519/jospt.2009.2831
  5. Kastner M, Straus SE, McKibbon KA, Goldsmith CH: The capture-mark-recapture technique can be used as a stopping rule when searching in systematic reviews. J Clin Epidemiol 2009;62(2):149-157. [2008 Aug 22 Epub ahead of print: PMID: 18722088]
  6. Thabane L, Goldsmith CH, Walter SD, Hanna S, Pullenayegum E: Development of a Biostatistical Collaboration Course in Health Sciences Research Methodology Program.  Journal of Statistics Education 2008;16(2):
  7. Wright FV, Rosenbaum PL, Goldsmith CH, Law M, Fehlings DL: How do Changes in Body functions and structures, activity, and participation relate in children with cerebral palsy. Developmental Medicine & Child Neurology 2008;50:283-289.  DOI: 10.1111/j.1469-8749.2008.0237.X
  8. Papanikolaou F, Goldsmith CH: Testing Quality Improvement Interventions.  Chapter in Clinics in Plastic Surgery.  A Thoma (Editor). 2008;35(2):297-303.
  9. Lovrics PJ, Cornacchi SD, Barnabi F, Whelan T, Goldsmith CH: The feasibility and responsiveness of the health utilities index in patients with early-stage breast cancer:  a prospective longitudinal study. Qual Life Res 2008;17:333-345. DOI: 10.1007/s11136-007-9305-2
  10. Bellamy N, Bell MJ, Pericak D, Goldsmith CH, Torrance GW, Raynauld J-P, Walker V, Tugwell PSL, Polisson R: BLISS Index for analyzing knee osteoarthritis trials data. J Clin Epidemiol 2007;60(2):124-132.

Search for citations for Dr. Goldsmith on PubMed