Health Research Methods, Evidence, and Impact

Stephen Walter

BSc, ARCS(London), PhD (Edinburgh), FRSC

Professor Emeritus, Department of Health Research Methods, Evidence, and Impact

Associate Member, Department of Mathematics and Statistics

Fellow, Royal Society of Canada (2013)
Fellow, American Statistical Association (1993)
Fellow, International Statistical Institute (1986)
Fellow, Royal Statistical Society (1971)
National Health Scientist (1982 -1999)
CIHR Senior Investigator (2000 – 2006)

Taiwan Science Council, Distinguished Scholar Award (2006).
Statistical Society of Canada, Inaugural Award for Impact of Applied and Collaborative Work (2008).
Inaugural Bernard Greenberg Award for Excellence in Methods Development and Application, North American Congress of Epidemiology (2011).
Winner, International Epidemiology Library Essay Contest (American College of Epidemiology and the Netherlands Royal Academy of Arts and Sciences; World Congress of Epidemiology, 2011).

905.525.9140 x 22406

Faculty of Health Sciences
McMaster University
CRL, Room 233
1280 Main Street West
Hamilton, ON
L8S 4K1


Academic Interests

Dr. Walter has collaborated with clinicians in internal medicine, evidence-based medicine, and developmental pediatrics, and with epidemiologists working in environmental health, cancer etiology and screening. He is currently interested in several areas of biostatistical methodology, including: design and analysis of research studies; risk assessment and communication; and evaluation of diagnostic and screening data. He has published over 400 papers on these topics in the biomedical literature.

Dr. Walter has acted as an Editor of the American Journal of Epidemiology, and as a Section Editor for the Wiley Encyclopedia of Biostatistics. He served as the Chair of Biostatistics in the International Clinical Epidemiology Network (INCLEN), and has been involved with the development of clinical epidemiology in Asia, Latin America and Africa. He is a past coordinator of the McMaster Health Research Methods program, and has worked with approximately 100 students at the Masters and Ph.D. level. He is also a Visiting Professor at the Universities of Sydney (Australia) and Tampere (Finland).

Selected Publications

  1. Walter SD, Ismaila AS, Cook DJ, Bhandari M, Tikkinen KAO, Guyatt GH (2013). Clinical experience may affect clinician compliance with assigned treatment in randomised trials.  J Clinical Epidemiology 66, 768-74.
  2. Walter SD, Riddell CA, Rabachini T, Villa LL, Franco EL (2013). Accuracy of p53 codon 72 polymorphism status determined by multiple laboratory methods: a latent class model analysis. PLOS One 8, e56430.
  3. Bassler D, Montori VM, Briel M, Glazziou P, Walter SD, Ramsey T, Guyatt G (2013).  Reflections on meta-analyses involving trials stopped early for benefit: is there a problem and if so, what is it? Statistical Methods in Med Research 22, 159-68.
  4. Walter SD, Sun X, Heels-Ansdell D, Guyatt G (2012). Treatment effects on patient-important outcomes can be small, even with large effects on surrogate markers. J Clinical Epidemiology 65, 940-45.
  5. Walter SD, Turner RM, Macaskill P, McCaffery KJ, Irwig L (2012). Optimal allocation of participants for the estimation of selection, preference and treatment effects in the two-stage randomised trial design. Statistics in Medicine 31, 1307-22.
  6. Walter SD, Macaskill P, Lord SJ, Irwig L (2012). Effect of dependent errors in the assessment of diagnostic or screening test accuracy when the reference standard is imperfect. Statistics in Medicine 31, 1129-1138.
  7. Walter SD, Ismaila AS, Devereaux PJ, for the SPRINT study investigators (2008). Statistical issues in the design and analysis of expertise-based randomized clinical trials. Statistics in Medicine 27: 6583-96.
  8. Walter SD, Marrett LD, From L, Hertzman C, Shannon HS, Roy P (1990). The association of cutaneous malignant melanoma with the use of sunbeds and sunlamps.  Amer J Epidemiology 131, 232-243.
  9. Hui SL, Walter SD. (1980) Estimating the error rates of diagnostic tests.  Biometrics 36, 167-171.
  10. Walter SD (1976). The estimation and interpretation of attributable risk in health research.  Biometrics 32, 829-849.

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