Clinical Epidemiology & Biostatistics
Feng Xie
BSc (Shanghai), MSc (Shanghai), PhD (Singapore)Assistant Professor, Department of Clinical Epidemiology & Biostatistics
Member, Program for Assessment of Technology in Health
Member, Centre for Evaluation of Medicines (CEM)
905.523.7284 x 5272
905.522.0568
fengxie@mcmaster.ca
Program for Assessment of Technology in Health (P.A.T.H)
25 Main Street West, Suite 2000
Hamilton, Ontario, Canada
L8P 1H1
Administrative Assistant: Donna Wilcockson
905.523.7284 x 5281
905.522.0568
wilcocks@mcmaster.ca
Academic Interests
Dr. Feng Xie is an Assistant Professor in the Department of Clinical Epidemiology and Biostatistics, McMaster University. Dr. Xie's primary interests include health technology assessment (HTA), methods in economic evaluations in health care including modeling and trial-based, health related quality of life and health utility measures. He is the Director of Health Technology Assessment Program (HTAP) in the PATH Research Institute. HTAP is the only academic centre of excellence in collaboration with the Canadian Agency for Drugs and Technologies in Health (CADTH) in conducting HTAs to support national policy makings. Dr. Xie is leading several HTAs with the Ontario Ministry of Health and Long Term Care (MOHLTC) to support reimbursement decision makings in Ontario.
Dr. Xie is an Associate Editor of the BMC Journal: Health and Quality of Life Outcomes and a member of the editorial board of Medical Decision Making, Journal of Pain Research and Journal of Inflammation Research. He is a member of Expert Reviewer Panel in the National Coordinating Centre for Health Technology Assessment (NCCHTA) and an external reviewer for the National Institute for Health Research HTA Programme Clinical Evaluations and Trials in the United Kindom. Dr. Xie is also a Pharmacoeconomics Expert Reviewer for MOHLTC. Dr. Xie received the Career Scientist Award of the MOHLTC in 2010. He has over 60 publications on peer-reviewed medical and HTA journals.
Dr. Xie's teaching activities in the Health Research Methodology Graduate Program at McMaster University include economic evaluation in health care, advanced economic modelling, statistical and methodological issues in randomized clinical trials. He is also lecturing/tutoring in the annual international workshop on HTA hosted by McMaster University and advanced economic modelling workshop jointly hosted by McMaster University, University of York, and University of Glasgow. Dr. Xie led a half-day short course on health utility measurement in the 2010 Society for Medical Decision Making annual meeting in Toronto.
Current HRM Graduate Students
Kuhan Perampaladas (MSc)
Brett Doble (MSc)
Pimwara Tanvejsilp (PhD)
Selected Publications
- Xie F, Lo NN, Tarride JE, O'Reilly D, Goeree R, Lee HP. Total or partial knee replacement? Cost-utility analysis in patients with knee osteoarthritis based on a two-year observational study. European Journal of Health Economics 2010;11(1):27-34.
- Xie F, Pullenayegum EM, Li SC, Hopkins R, Thumboo J, Lo NN. Use of a disease-specific Instrument in economic evaluations: mapping Western Ontario and McMaster Universities Osteoarthritis Index onto the EQ-5D utility. Value in Health 2010;13(8):873-8.
- Xie F, Ye H, Zhang Y, Liu X, Lei T, Li SC. Extension from inpatients to outpatients: validity and reliability of the Oxford Knee Score in measuring health outcomes in patients with knee osteoarthritis. International Journal of Rheumatic Diseases 2011;14(2):206-10.
- Chow BJW, Freeman MR, Bowen JM, Levin L, Hopkins RB, Provost Y, Tarride J-E, Dennie C, Cohen EA, Marcuzzi D, Iwanochko R, Moody AR, Paul N, Parker JD, O'Reilly DJ, Xie F, Goeree R. Ontario Multi-detector Computed Tomographic Coronary Angiography Study (OMCAS): field evaluation of diagnostic accuracy. Archives of Internal Medicine 2011;171(11):1021-1029.
- Johnston BC, Thorlund K, Schunemann HJ, Xie F, Murad MH, Montori VM, Guyatt GH. Improving the interpretation of quality of life evidence in meta-analyses: the application of minimal important difference units. Health and Quality of Life Outcomes 2010;8:116.
- Gaebel K, McIvor RA, Xie F, Blackhouse G, Robertson D, Assasi N, Hernandez P, Goeree R. Triple Therapy for a Management of COPD: A Review. COPD 2011 8(3):206-243.
- von Keyserlingk C, Hopkins R, Anastasilakis, Toulis K, Goeree R, Tarride J-E, O'Reilly D, Xie F. Clinical efficacy and safety of denosumab in postmenopausal women with low bone mineral density and osteoporosis: A meta-analysis. Seminars in Arthritis and Rheumatism 2011 (ePub May 24 2011)
- Xie F, Oremus M, Gaebel K, Measuring Health-related Quality-of-life for Alzheimer's Disease Using the General Public. Quality of Life Research 2011 (forthcoming)