McMaster University

Firestone Institute for
Respiratory Health

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St Jospehs Hospital FIRH

Firestone Institute for Respiratory Health

Welcome to the FIRH!

The Firestone Institute for Respiratory Health (FIRH) is based out of St. Joseph's Healthcare in Hamilton, Ontario, Canada and is affiliated with McMaster University. Clinical, research and educational activities are integrated and largely collaborative within the FIRH. The intent of this institute is to provide optimal patient care through clinical practice, translational research and the training of health care professionals.


Recognizing Four Papers that Represent Four Breakthroughs in Asthma Research

St. Joe's congratulates our Firestone Institute for Respiratory Health on a remarkable achievement: 4 research papers just published in the . This research will transform how we treat mild and severe asthma. Learn more: |

Recognizing Four Papers


International Study Suggests Alternative Treatment for Mild Asthma - Dr. Paul O'Byrne

A large international study led by a McMaster researcher has found a patient-centric treatment that works for people with mild asthma.

People with mild asthma are often prescribed a daily treatment regimen, but up to 80 per cent do not follow the routine, using inhalers only when they have an asthma attack. Now the researchers have found an as-needed combined-drug inhaler is a viable treatment option.

Paul O'Byrne is the principal investigator on the study that suggests an inhaler with a combination of budesonide, a steroidthat controls inflammation, and formoterol,a beta2-agonist that helps to open airways and make breathing easier, may be an alternative to conventional treatment strategies.

Article - International Study Suggests Alternative Treatment for Mild Asthma


2018 FHS Research Plenary Postdoctoral Fellow Publication Award - Dr. Manali Mukherjee

2018 FHS Research Plenary Postdoctoral Fellow Publication Award - Dr. Manali Mukherjee

Dr. Manali Mukherjee, Post-Doctoral Fellow working alongside Dr. Param Nair, was selected to receive the 2018 FHS Research Plenary Postdoctoral Fellow Publication Award for publications such as:

Weight-adjusted Intravenous Reslizumab in Severe Asthma with Inadequate Response to Fixed-Dose Subcutaneous Mepolizumab.

Mukherjee M, Aleman Paramo F, Kjarsgaard M, Salter B, Nair G, LaVigne N, Radford K, Sehmi R, Nair P. Am J Respir Crit Care Med. 2018 Jan 1;197(1):38-46. doi: 10.1164/rccm.201707-1323OC.

Sputum autoantibodies in patients with severe eosinophilic asthma.

Mukherjee M, Bulir DC, Radford K, Kjarsgaard M, Huang CM, Jacobsen EA, Ochkur SI, Catuneanu A, Lamothe-Kipnes H, Mahony J, Lee JJ, Lacy P, Nair P. J Allergy Clin Immunol. 2018 Apr;141(4):1269-1279. doi: 10.1016/j.jaci.2017.06.033. Epub 2017 Jul 24.

Dr. Mukherjee has also been awarded a 2 year CIHR Post-Doctoral Award. Congratulations on these much deserved achievements!


2018 FHS Research Plenary Graduate Student Teaching Assistant Excellence Award - Dr. Kiho Son

Dr. Kiho Son, Graduate Student working alongside Dr. Luke Janssen, was selected to receive the 2018 FHS Research Plenary Graduate Student Teaching Assistant Excellence Award for his work with the BioPharmacology 3B06 course. Kiho was nominated by the very students he helped teach. Dr. Son also has just been awarded an Ontario Graduate Fellowship. Congratulations on these these much deserved achievements!