McMaster University

McMaster University

Arthroplasty Trial Publications After Registration in

We would like to share with you a publication evaluating the publication rates of arthroplasty trials registered with (CTG).

Smith HN, Bhandari M, Mahomed NN, Jan M, Gandhi R. Comparison of Arthroplasty trial Publication after Registration in J Arthroplasty 2012; 27(7): 1283-1288


In 2005, the International Committee of Medical Journal Editors established a mandatory trial registration before study enrollment for publication in member journals. Our primary objective was to evaluate the publication rates of arthroplasty trials registered with (CTG). We further aimed to examine the consistency of registration summaries with that of final publications. We searched CTG for all trials related to joint arthroplasty and conducted a thorough search for publications resulting from registered closed trials. Of 101 closed and completed trials, we found 23 publications, for an overall publication rate of 22.8%. Registration of arthroplasty trials in CTG does not consistently result in publication or disclosure of results. In addition, changes are frequently made to the final presentation of the data that are not reflected in the trial registry.

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