McMaster University

McMaster University

Biologic Treatments for Hip Disorders: A Focus On Platelet-Rich Plasma

We are pleased to share with you a recent publication in Operative Techniques in Orthopaedics. This publication is entitled "Biologic Treatments for Hip Disorders: A Focus On Platelet-Rich Plasma".

Please find access to the full-version of the article click here.

Dzaja I, Kay J, de SA, D, Simunovic N, Ayeni OR. Biologic Treatments for Hip Disorders: A Focus On Platelet-Rich Plasma. Oper Tech Orthop. March 16. [Epub ahead of print] DOI:10.1053/j.oto.2015.11.003

Abstract

The purpose of this systematic review was to assess the role of platelet-rich plasma (PRP) in the treatment of various hip conditions (e.g. avascular necrosis, osteoarthritis, femoroacetabular impingement, labral tears). The Medline, Embase, and PubMed databases were searched on August 5, 2015 for English-language studies that addressed PRP use in any hip condition. The studies were systematically screened by two reviewers and data abstracted in duplicate. There were 11 eligible studies (five randomized controlled trials, one prospective comparative study, two case series, and three case reports) reporting on 765 patients. The mean follow-up was 17.9 months (range: 1 – 48 months). All randomized controlled trials and the prospective comparative study data demonstrated no benefit to PRP use in reviewed hip conditions. All case series’ and case reports demonstrated favourable outcomes with PRP use. There was a low complication rate, with 12 reported complications in the 765 patients (1.6%). Although use of PRP appears to be safe, there does not appear to be any significant benefit for its use in this patient population.


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