Left to right:
Dr. Mary Margaret Chiavaras, McMaster University (Principal Investigator)
Dr. Mohit Bhandari, McMaster University (Co-Investigator)
Dr. Jon Jacobson, University of Michigan (Co-Investigator)
MacOrtho is pleased to announce that the IMpact of Platelet Rich plasma OVer alternative therapies in patients with lateral Epicondylitis (IMPROVE) study reached its enrollment target of 100 patients this week! We would like to thank all collaborators for their contributions to this milestone and for their continued support in this very important trial.
All patients were recruited by the Hamilton General Hospital (Ontario, Canada) and the University of Michigan (Michigan, United States). Follow-up for IMPROVE will continue for a period of 2 years and data analysis will follow upon the completion of data collection.
The principal objectives of the IMPROVE trial include assessing the efficacy of PRP versus whole blood versus dry needle tendon fenestration versus physical therapy alone on: 1) pain in individuals with lateral epicondylitis as measured by relief of pain, 2) health-related quality of life, range of motion, infection, and tendon rupture, and 3) ultrasound appearance of the common extensor tendon (echogenicity, thickness, hyperemia).