McMaster University

McMaster University

Viscosupplementation for knee osteoarthritis

MacOrtho is pleased to announce the most recent publication in the Journal of Long-Term Effects on Medical Implants. This publication is entitled “Viscosupplementation for knee osteoarthritis: current evidence and recommendations.”

To read more,click here to access the full-version of the article.

Please click here to access more articles in the issue.

Evaniew N, Hanson B, Winemaker M. Viscosupplementation for knee osteoarthritis: current evidence and recommendations. J Long Term Eff Med Implants. 2013;23(2-3):151-9.


Osteoarthritis (OA) is the most common joint disorder worldwide and is a leading cause of pain and disability. Appropriate management of younger patients with milder disease remains a challenging area of intense research. Viscosupplementation attempts to restore the biomechanical and biochemical functions of normal synovial fluid hyaluronic acid. Several preparations with varying characteristics are currently available. The literature suggests a small benefit and relative safety, but several recent large meta-analyses have reported conflicting results. Major clinical guidelines provide inconclusive recommendations. Viscosupplementation may be a viable option in younger patients with milder OA where other non-operative modalities are also only modestly successful, but further investigation is clearly warranted. Limitations due to study heterogeneity, outcome reporting, and bias can each be addressed with improved research methodology.

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