Microbial diseases, in particular the increasingly prevalent antibiotic-resistant pathogens, constitute major threats to human health. The McMaster University Antimicrobial Research Centre aims to attack these diseases by bringing together a broad spectrum of research interests.
The Department of Biochemistry and Biomedical Sciences at McMaster University is one of the top centers for life sciences research in North America. The research under way in the laboratories of our faculty members include all of the important areas of academic biomedical research as well as areas of direct relevance to the pharmaceutical industry.
The Brain-Body Institute (BBI) is a joint research initiative between St. Joseph's Healthcare, Hamilton, and McMaster University and was created to advance the understanding of relations between the brain, the nervous system and bodily disorders. Clinical and basic scientists in this multidisciplinary Institute study the interaction and impact of environmental factors, including stress, early life experiences and early microbial exposure on the brain and nervous system.
CAIRN is composed of scientists,
parents, early childhood educators, psychiatrists, pediatricians, nurses, occupational therapists,
speech/language pathologists, policy makers and more – all working together to develop effective,
evidence-based early diagnostic methods and treatments for children with autism spectrum
disorders.
Research programs at
CanChild concentrate on children and youth with disabilities and their families within
the context of the communities in which they live. The focus of research conducted by CanChild
is broad, and includes children and youth with physical, developmental, and/or communicative needs
who require rehabilitation services, as well as their families.
CLARITY represents the formal alliance of a group of researchers who have enjoyed a long-standing and fruitful collaboration. The seven CLARITY faculty members -- Gordon Guyatt, Brian Haynes, Deborah Cook, Maureen Meade, PJ Devereaux, Holger Schünemann and Mohit Bhandari -- participated in an inaugural group meeting in 2003. Through formal collaboration, Clarity's clinical advances through research and information translation has been pivotal in creating a renewed sense of spirit, vision and commitment.
The Centre for Evaluation of Medicines is a multi-disciplinary resource that provides expertise in clinical pharmacology and toxicology, economics, health policies, behavioral sciences, information technology, research design and biostatistics. The CEM is a neutral and objective source for information and leading edge analyses in the fields of therapeutics and health policy interventions.
The Centre for Health Economics
and Policy Analysis is an interdisciplinary research centre that is committed to producing
high-quality, original, socially relevant research in health economics and health policy
analysis, and to disseminating research evidence to decision makers in the health sector.
Research spans a broad range of topics, check out their website for more details.
The Centre for Microbial Chemical Biology (CMCB) supports cross-disciplinary research between scientists in the departments of biochemistry and biomedical sciences, biology, chemistry and chemical biology, and geography and earth sciences, focusing on new applications in infection control from diagnostics to new drug discoveries.
The Centre for Minimal Access
Surgery provides state of the art facilities, education and training in minimally invasive
procedures for surgeons and nurses. The facility promotes and supports world-class research
into outcome and development of new minimally invasive procedures. CMAS has developed a
unique partnership with industry to further the development and application of minimally
invasive surgical technique.
The Centre of Knowledge on Healthy Child Development provides 'plain language" summaries of the latest research, including evidence-based treatments, for a wide range of child and youth mental health problems.
The Department of Clinical Epidemiology and Biostatistics (CE&B) is a "research-intensive department in a research-intensive university." CE&B conducts world-leading research into the nature, prevention and management of health care problems. They also conceive, design, organize and implement ground-breaking clinical trials.
COMPETE II is the second phase
of COMPETE, a 3 year research project which involved a network of primary care practices
in the Hamilton-Wentworth area. The mission of COMPETE II is to develop an effective,
integrated clinical decision-support tool for patients and health care providers. In
collaboration with its partners and federal and provincial lead health organizations,
this project aims to provide a clear pathway to an integrated national electronic health
record network.
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The Effective Public Health Practice Project (EPHPP), part of McMaster University’s School of Nursing, conducts systematic reviews on the effectiveness of public health interventions and summarizes recent, high-quality reviews produced by others. The project, funded by the Ministry of Health and Long-Term Care and the City of Hamilton Public Health Services, aims to foster evidence-based practice and decision making in public health.
The Evidence-based Practice
Centre (EPC) at McMaster University is one of three Evidence-based Practice Center designated
by the Agency for Health Research and Quality. The EPC promotes research that supports the
development, dissemination, and application of evidence to clinical practice and policy as
well as student involvement and training for better understanding of the role of evidence
in health care decision-making.
Father Sean O'Sullivan Research Centre
The Father Sean O'Sullivan Research Centre was established in 1993 by St. Joseph's
Hospital in Hamilton and is affiliated with the Faculty of Health Sciences at McMaster
University. The Centre has developed world-class research programs in the areas of
chest & lung, optimal drug therapy, urology & nephrology and musculoskeletal
research.
The Farncombe Family Digestive Health Research Institute is an integrated group of clinical and basic scientists dedicated to understanding the causes of chronic digestive diseases. The institute is focused on developing new strategies for the diagnosis, treatment and prevention of intestinal diseases such as Crohn’s disease and colitis, which will have global benefits.
The Firestone Institute for Respiratory
Health is a world class respiratory program providing comprehensive
patient care, research and education. The program is comprised of an
outpatient service, an inpatient unit managing severe or chronic
respiratory diseases and the regional thoracic (chest) surgery program.
Established in 1988, the Geriatric Research Group (GRG) is affiliated with both the
Hamilton Health Sciences and McMaster University's Department of Medicine.
They are committed to the development and testing of methodologies for the assessment
and treatment of dementia, the education and promotion of the elderly, of individuals'
rights and autonomy, and of ethical medical practice.
The Hamilton Centre for Kidney Research (HCKR) is directly affiliated with the Department of Medicine’s Division of Nephrology located at St. Joseph's Healthcare. The mandate of the HCKR is to combine expertise in clinical and basic research to reduce the risk of kidney disease and its complications.
St. Joseph’s Healthcare Hamilton is a fully-accredited teaching hospital and academic health sciences centre affiliated with McMaster University.
The health-evidence.ca website is a free, searchable online registry that provides quality research evidence to public health decision makers. The project, developed by researchers in McMaster’s School of Nursing, was created by funds from the Canadian Institutes of Health Research and is supported in part by the National Collaborating Centres for Public Health and the City of Hamilton Public Health Services.
The Health Information Research Unit (HIRU) conducts
research in the field of health information science and is dedicated to the generation
of new knowledge about the nature of health and clinical information problems, the
development of new information resources to support evidence-based health care, and
the evaluation of various innovations in overcoming health care information problems.
The Health Utilities Group (HUG) is a
multi-disciplinary group of researchers and scientists based in the Department
of Clinical Epidemiology and Biostatistics (CE & B) at McMaster University. HUG develops and applies systems for measuring the health status
and health-related quality of life of individuals, clinical groups and general
populations. Over the past 20 years HUG members have developed the Health
Utilities Index (HUI) ‘family’ of classification and preference-based
scoring functions.
The vision of MOBIX, the McMaster
Institute for Molecular Biology and Medicine, is to develop a world-class
centre for life science and translational research. MOBIX makes use of
the most recent advances in basic and applied molecular biology and develops
these findings into diagnostic and therapeutic interventions in human health.
MOBIX consists of a series of centres, set up within the institute, each
with its own experimental and development goals and all sharing the common
vision.
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Researchers at the McMaster Child Health Research Institute are looking beyond medical treatments of individual conditions to explore the deeper connections between childhood illness and long-term health. The mandate of the MCHRI is to foster collaborative research and educational efforts dedicated to understanding the forces and experiences that shape human development and health as children and youth with complicated lives and their families move through the life-course.
The mission of the McMaster Immunology Research Centre is to investigate, create and implement approaches utilizing the delivery of genes as therapeutic agents in the treatment of human and animal disease. The Centre is focused on developing novel cures for cancer, inflammatory diseases and infectious diseases using state-of-the-art gene transfer technology coupled with the most recent information derived from the application of genomics.
The McMaster Institute of Environment &
Health has mobilized interdisciplinary, collaborative research projects in
such areas as the convergence of health and environmental ethics, environment
and human reproduction (especially endocrine modulators), environmental
cancer epidemiology, environmental health policy, environmental quality,
respirable air particulates, social-psychological effects of potential
and perceived environmental threats, and the social construction of
chemical toxicity.
A McMaster Institute for Surgical Invention, Innovation and Education was established in 2005. Offered jointly by the Faculty of Health Sciences and St. Joseph's Healthcare Hamilton, the research institute will include the Centre for Minimal Access Surgery (CMAS).
McMaster Institute of Urology
The McMaster
Institute of Urology at St. Joseph's Healthcare is a template for the
development of a surgical division in
the new millennium. It provides excellence in patient care, research and
education. The Institute been developed with the idea of involving allied health professions, especially nursing in the care of these patients.
The McMaster Transfusion Research Program
(MTRP) is a joint partnership between the Canadian Blood Services (CBS)
and McMaster University, Faculty of Health Sciences. MTRP is dedicated
to the advancement of innovative evidence-based diagnostic, clinical,
and therapeutic practices in Transfusion Medicine. Their ultimate goal
is to provide scientific evidence that will inform transfusion practice a
nd enhance the safety of blood recipients.
The Michael G. DeGroote Institute for Infectious Disease Research (IIDR) was established in 2007 through an unprecedented gift from Michael G. DeGroote. The IIDR is founded on principles of interdisciplinary collaboration, research excellence, and commitment to training the next generations of infectious disease researchers and clinicians. The IIDR members are from 3 Faculties and 8 Departments at McMaster University. Over 180 Graduate students, post-doctoral and clinical fellows research various programs funded by provincial, national, and international peer reviewed agencies as well as the private sector.
As a result of the DeGroote family gift, a world-class
institute will be created at McMaster to focus the clear, piercing light of science and
medicine on this age-old problem. Encompassing an array of technologies, disciplines
and specialties, the institute will explore the causes of a number of different types
of pain, develop new strategies for its prevention, diagnosis and management and develop
innovative care for patients.
The Microcapsule Gene Therapy Group is based at McMaster University. Their
research looks at a non-viral strategy for gene therapy.
The National Collaborating Centre for Methods and Tools (NCCMT), hosted by McMaster University’s School of Nursing, is one of six National Collaborating Centres funded by the Public Health Agency of Canada. The mission of NCCMT is to improve access to and use of evidence-based methods and tools in public health policy and practice.
The Nursing Education
Research Unit (NERU) began in January 1995 and is a part of the McMaster University School of
Nursing. Their purpose is to promote, foster and conduct educational research, in particular,
nursing education research in order to enhance the teaching and learning process.
The Nursing Effectiveness, Utilization and Outcomes Research Unit (NRU) is a collaborative
project of the University of Toronto, Faculty of Nursing and McMaster University, School of
Nursing that has been recognized internationally, nationally, and provincially for their
comprehensive team approach to problem identification and resolution.
The Offord Centre for Child Studies is researching why some young people are
able to overcome enormous obstacles and grow up to be well-adjusted and productive
adults whereas others cannot. The Centre is also developing, implementing and
assessing a number of promising, cost-effective, early interventions to treat
and prevent destructive emotional and behavioural problems in our children
and youth.
The Population Genomics Program (PGP) mobilizes McMaster’s expertise and resources in population health, genomics, clinical trials and health-research methodology to investigate the influences of gene-gene and gene-environment interactions on disease. It fosters interdisciplinary collaborations among clinical researchers and basic scientists to marshal new insights and discoveries in the burgeoning field of population genomics at McMaster.
The Population Health Research Institute (PHRI) provides a forum for the conduct of
large international clinical trials, population health studies, and studies in outcomes
research. While its primary role is to provide leadership in international health
research, the PHRI also plays an active role in the education of individual researchers,
and in building capacity internationally for the development of global research programs.
The Program for Educational Research and Development is a component of the
Academic Services unit of the Faculty of Health Sciences, dedicated to the
advancement of research and scholarship in health sciences education in the
faculty, the university and beyond.
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The Smooth Muscle Research Program (SMRP) provides a common forum for researchers to
share ideas and expertise to promote multidisciplinary research on smooth muscle
structure and function in health and disease.
The St. Joseph’s Health System (SJHS) Research Network represents a
program of Father Sean O’Sullivan Research Center that brings research
expertise and opportunities across all of the system facilities. The research
program examines the relationship of health and social services for the older
adult and their family caregivers in terms of their organization, accessibility,
and process of care. The emphasis is on quality of life outcomes of older adults and
their family caregivers.
The McMaster Stem Cell and Cancer Research Institute (SCC-RI) will investigate the parallels between the behavior of human stem cells and the initiation of human cancer. This research has the potential to alleviate the suffering of patients-and save lives-through the development of therapies to repair or replace healthy cells damaged by disease and by studying human stem cells in pre-clinical models that include the testing of new cancer drugs. The fundamental stem cell research being conducted at the SCC-RI will also open up exciting possibilities for biomedical applications including new gene and drug discovery, particularly for conditions such as Leukemia and other cancers, Parkinson's, diabetes, Alzheimer's and spinal cord injury.
The Supportive Cancer Care Research Unit is committed to the improvement
of supportive care services provided to cancer patients and their families
through research, and research transfer activities. The ongoing research
carried out by the Unit significantly enhances the identification of
supportive care needs of cancer patients and facilitates the development,
evaluation, and coordination of supportive care services to help meet
those needs.
The Surgical Outcomes Research Centre (SOURCE) was
founded in 1996 when a need was recognized to increase the amount and quality of
surgical outcomes. SOURCE currently has 39 members from four Hamilton hospitals,
and is providing research assistant resources for start-up projects for its members.
Other SOURCE activities include an evidence-based surgery article series published
in the Canadian Journal of Surgery and the evidence-based surgery training workshops.
The System Linked Research Unit is a group
of university-based researchers and community partners dedicated to creating
new solutions for problems that challenge health and social services. The
research team is based at McMaster University. The Unit was launched in 1991,
with funding from the Ontario Ministry of Health (now Health and Long-Term Care),
to test out new and innovative ways of delivering health and social services for
vulnerable people.
The Thrombosis & Atherosclerosis Research Institute (TaARI) (formerly the Henderson Research Centre) was established in 1988 as a joint initiative
of the Hamilton Civic Hospitals (now part of the Hamilton Health Sciences) and
McMaster University. Its mission is to conduct research into the pathogenesis,
prevention, diagnosis and treatment of thrombosis and vascular disease and to
provide a resource for key areas of research as outlined in the mission statement
of the Hamilton Health Sciences.
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The Work Function Unit (WFU) is based at McMaster University's School of Rehabilitation Science. They are a group of researchers, clinicians and academics conducting applied research, education and consultation in the area of work and human function.
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