Clinical Immunology & Allergy Residency Program

Rotation-Specific Goals and Objectives for Bone Marrow Transplantation Rotation

During the Bone Marrow Transplantation rotation, the resident will achieve the following in their role as:


  1. Understand major histocompatibility complex structure and functions
  2. Develop knowledge regarding the basic science principles of graft rejection and tolerance
    1. Understand alloreactive T cell activity and recognition of alloantigens
  3. Demonstrate knowledge of indications for bone marrow transplantation, both autologious and allogeneic
  4. Demonstrate knowledge of the management of complications of transplant, including rejection and infection
  5. Understand the principles of prevention, recognition and treatment of allograft rejection
  6. Understand the pathophysiology, presentation, prevention and management of graft vs host reactions (acute and chronic)
  7. Demonstrate knowledge of conditioning regimens used in bone marrow transplant for different indications
  8. Become familiar with immunomodulatory medication commonly used in transplantation
  9. Describe the principles and methodology of histocompatibility typing


  1. Develop therapeutic relationship with bone marrow transplant recipients and donors
  2. Collect relevant information and synthesize the significant history from patients and families
  3. Listen effectively to information provided by patients, their families and other health professionals involved in the care of the individual patients
  4. Deliver adequate information to the patients regarding their disease and treatment
  5. Provide appropriate and comprehensive advice as well as instructions for therapies


  1. In consultation with the hematology team and other health care professionals involved, develop a comprehensive care-plan for the patient
  2. While demonstrating the ability to incorporate the opinions of the hematology team, enhance and contribute allergy/clinical immunology specific expertise to the team


  1. Understand the function of the bone marrow transplantation team as part of a health care organization
  2. Understand the role of different health care practitioners and allied health members within the bone marrow transplantation team
  3. Understand the economic impact associated with bone marrow transplantation for different indications
  4. Make appropriate decisions when allocating finite health care resources
  5. Prioritize and execute tasks in an efficient manner
  6. Utilize information technology to optimize patient care, maintain life-long learning


  1. Identify the important determinants of health including environmental cultural, social and economic factors on bone marrow transplant donors and recipients
  2. Contribute effectively to improve the health of patients and communities by adapting the management according to the patient’s medical history and social circumstances


  1. Critically appraise sources of medical information with regards to bone marrow transplantation, particularly those related to bone marrow transplant in immunodeficiency


  1. Deliver the highest quality care with integrity, honesty and compassion
  2. Exhibit appropriate personal and interpersonal professional behaviors
  3. Respect diversity of age, gender, disability, intelligence and socioeconomic status
  4. Practice medicine ethically, consistent with the obligations of a physician
  5. Exhibit punctuality