James Douketis


Professor, Division of Hematology and Thromboembolism, Department of Medicine

Associate Director, Clinical Teaching Unit, St. Joseph's Hospital

Staff Physician, Clinical Thromboembolism and General Internal Medicine Services,
St. Joseph’s Hospital

Education and Professional Standing

Current Position

Professional and Scholarly Associations

Community Activities

Educational Activities

Editorial Activities

Research Interests

Selected Publications

  1. Douketis JD, Kearon C, Bates S, et al. The risk of fatal pulmonary embolism in patients with treated venous thromboembolism. JAMA 1998;279:458-62.
  2. Douketis JD, Feightner JW, Attia J, et al. Periodic health examination, 1999 update: Detection prevention and treatment of obesity. CMAJ 1999;160:513-24.
  3. Douketis JD, Foster GA, Crowther MA, et al. Clinical risk factors and timing of recurrent venous thromboembolism during the initial 3 months of anticoagulant therapy. Arch Intern Med 2000;160:3431-6.
  4. Douketis JD, Kinnon K, Crowther MA. Anticoagulant effect at the time of epidural catheter removal in patients receiving low-molecular-weight heparin and continuous epidural analgesia after orthopedic surgery. Thromb Haemost 2002;88:37-40.
  5. Douketis JD. Perioperative anticoagulant management in patients who are receiving oral anticoagulant therapy: A practical guide for clinicians. Thomb Res 2002;108:3.
  6. Linkins L, Choi P, Douketis JD. What is the clinical impact of bleeding in patients with venous thromboembolism who are receiving oral anticoagulant therapy? An assessment of case-fatality and risk of major bleeding. Ann Intern Med 2003;139:893-900.
  7. Douketis JD, Johnson JA, Turpie AG. Low-molecular-weight heparin as bridging anticoagulation in patients who require temporary interruption of warfarin for an elective surgical or invasive procedure. Arch Intern Med 2004;169:1319-26.
  8. Douketis JD, Julian JA, Kearon C, et al. Does the type of hormone replacement therapy influence the risk of deep vein thrombosis? A prospective case-control study. J Thromb Haemost 2005;5:943-8.
  9. Douketis JD, Woods K, Foster GA, et al. Bridging anticoagulation with low-molecular-weight heparin after interruption of warfarin therapy is associated with a residual anticoagulant effect prior to surgery. Thromb Haemost 2005;94:528-31.
  10. Lau DC, Douketis JD, Morrison KM, et al. 2006 Canadian clinical practice guidelines on the management and prevention of obesity in adults and children. CMAJ 2007;176:S1-13.
  11. Douketis JD, Leeuwenkamp O, Grobara P, et al. The prevalence and prognostic significance of elevated cardiac troponins in patients with submassive pulmonary embolism. J Thromb Haemost 2005;3:50.
  12. Douketis JD, Macie C, Cuddy K, et al. Canadian Task Force on Preventive Health Care Recommendation Statement: Non-surgical Treatment of Obesity. Can Fam Physician 2006;52:1576-8.
  13. Dentali F, Douketis JD, Gianni M, et al. Anticoagulant prophylaxis to prevent symptomatic venous thromboembolism in hospitalized medical patients. Ann Intern Med 2007;146:278-88.
  14. Douketis JD, Gu CS, Schulman S, et al. The risk for fatal pulmonary embolism after discontinuing anticoagulant therapy for venous thromboembolism. Ann Intern Med 2007 (in press).
  15. Douketis JD, Berger PB, Dunn AS, Jaffer A, Spyropoulos AC, Becker R, Ansell J.
    The perioperative management of antithrombotic therapy: ACCP Evidence-Based Clinical Practice Guidelines (8th Edition). Chest 2008 (in press).
  16. Douketis J, Cook D, Meade M, Guyatt G, Geerts W, Skrobik Y, et al. Prophylaxis against deep vein thrombosis in critically ill patients with severe renal insufficiency with the low-molecular-weight heparin dalteparin: An assessment of safety and pharmacodynamics
    The DIRECT (Dalteparin’s Influence on REnally Compromised anti-Ten-A) Study. Arch
    Intern Med 2008 (in press).
  17. Spyropoulos AC, Douketis JD. Guidelines for antithrombotic therapy: Periprocedural management of antithrombotic therapy and use of bridging anticoagulation. Int Angiol 2008 (in press).

Dr. Douketis lives in Hamilton with his wife and 2 boys and is a cellist with Symphony Hamilton.