Division of Hematology & Thromboembolism

Howard H.W. Chan

M.B.Ch.B., M.Sc., FRCP(C)

Assistant Professor, Division of Hematology & Thromboembolism, Department of Medicine

 

 

Education and Professional Standing

  • M.Sc., Medical Sciences (2006)
  • Canadian Blood Service Transfusion Research Fellowship (2004)
  • FRCP (C), Internal Medicine (2002)
  • M.B.Ch.B. The Chinese University of Hong Kong (1987)

Research Interests

Dr. Howard Chan is an Assistant Professor at McMaster University in the Department of Medicine in the Division of Hematology. He received M.B.Ch.B. at The Chinese University of Hong Kong in 1987. He had 6-year oncology training at the Prince of Wales Hospital in Hong Kong. He immigrated to Canada in 1993 and recertified through International Medical Graduate (IMG) program. Dr. Chan then did internal medicine and hematology training at McMaster University in Hamilton. After that, Dr. Chan was a fellow in Transfusion Medicine Research Program, funded by Canadian Blood Service. He obtained M.Sc. in Medical Sciences in 2006.

Dr. Chan’s overall research interest is the pathophysiology of thromboembolism, focusing on the interactions of fibrinogen with divalent cations and other proteins. His current research activities are in the following areas:

  1. effects of zinc on fibrinogen and heparinheparin co-factor in the treatment of thromboembolism
  2. autoimmunity of glucose-regulated protein 78

These researches involve studies at the levels of molecular biology, protein biochemistry, cell biology and experimental animal models.

Dr. Chan’s recent publications include reviews in “Mechanisms in Hematology” and a peer-review paper of the works on fibrin-bound thrombin. The results of the study were selected for an oral presentation in a special symposium in American Society of Hematology 2007.