Division of Hematology & Thromboembolism

Jane Catharine Moore

MLT, ART, BSc

Assistant Professor, Division of Hematology and Thromboembolism,
Department of Medicine

 

 

Education and Professional Standing

  • Registered Medical Technologist, Mohawk College (1973-1975)
  • Advanced Registered Technologist, Immunohematology, Canadian Society of Lab. Technologists (1979-1980)
  • B.Sc. – Life Science, McMaster University (1988-2000)

Research Interests

Assist establishment of a substantial serum and plasma bank (ITP, HIT, TTP) for varied studies.

Participate in studies related to Immune Thrombocytopenia, Heparin Induced Thrombocytopenia, Thrombotic Thrombocytopenic Purpura, and von Willebrand Factor Abnormalities associated with Gastrointestinal Angiodysplasia.

Coordination of medical research elective for Hematology residents, Graduate Medical Education.

Selected Publications

  1. Kelton JG, Moore J, Gauldie J, Neame PB, Hirsh J, Tozman E. The development and application of a serum assay for platelet-bindable IgG (S-PBIgG). J Lab Clin Med 98:272-279, 1981.
  2. Kelton JG, Meltzer D, Moore J, Giles AR, Wilson WE, Barr R, Hirsh J, Neame PB, Powers PJ, Walker I, Bianchi F, Carter CJ. Drug-induced thrombocytopenia is associated with increased binding of IgG to platelets both in vivo and in vitro. Blood 58:524-529, 1981.
  3. Kelton JG, Keystone J, Moore J, Denomme G, Tozman E, Glynn M, Neame PB, Gauldie J, Jensen J. Immune-mediated thrombocytopenia of malaria. J Clin Invest 71:832-836, 1983.
  4. Kelton JG, Moore J, Santos A, Sheridan D. Detection of platelet-agglutinating factor in thrombotic thrombocytopenic purpura. Ann Intern Med 101:589-593, 1984.
  5. Kelton JG, Moore JC, Murphy WG. Studies investigating platelet aggregation and release initiated by sera from patients with thrombotic thrombocytopenic purpura. Blood 69:924-928, 1987.
  6. Murphy WG, Moore JC, Barr RD, Pal MKR, Kelton, JG. Relationship between platelet aggregating factor and von Willebrand factor in thrombotic thrombocytopenic purpura. Br J Haematol 66:509-513, 1987
  7. Murphy WG, Moore JC, Kelton JG. Calcium-dependent cysteine protease activity in the sera of patients with thrombotic thrombocytopenic purpura. Blood 70:1683-1687, 1987.
  8. Kelton JG, Moore JC, Murphy WG. The platelet aggregating factor(s) of thrombotic thrombocytopenic purpura. Prog Clin Biol Res 337:141-149, 1990.
  9. Moore JC, Murphy WG, Kelton JG. Calpain proteolysis of von Willebrand factor enhances its binding to platelet membrane glycoprotein IIb/IIIa: an explanation for platelet aggregation in thrombotic thrombocytopenic purpura. Br J Haematol 74:457-464, 1990.
  10. Jaeschke R, Irvine EJ, Moore JC, Kelton JG. Campylobacter jejuni and thrombotic thrombocytopenic purpura. Can J Gastroenterol 4:154-156, 1990.