Division of Respirology
Gail Marie Gauvreau
BSc, MSc, PhD
Research Interests
- Airway Inflammation
- Allergic Mechanisms
- Inflammatory cell activation
- Receptor regulation/signaling
- Leukotriene biology
Awards and Distinctions
- CFI New Opportunities Fund Award (2004)
- Department of Medicine Career Award (2003-2006)
Funding
- Ontario Thoracic Society: "Airway Inflammation in COPD: A cross sectional study comparing inflammatory features on sputum analysis" (07/04 - 06/05)
- Ontario Thoracic Society: "Airway Inflammatory Cells – Expression of TH2 genes and regulation by inhaled steroids" (07/05 - 06/06)
- Glaxo Smith Kline, Altana Pharma, ONO Pharmaceuticals, Pfizer Canada, Boehringer Ingleheim: Multi-center clinical trials in asthma and COPD (09/03 - present)
Selected Publications
- Expression of functional cysteinyl leukotriene receptors by human basophils J Allergy Clin Immunology 2005; 116:80-7.
- The Effect of Cysteinyl Leukotrienes on Growth of Eosinophil Progenitors from Peripheral Blood and Bone Marrow of Atopic Subjects. J Allergy Clin Immunol. 2002; 110:96?101.
- Differences in Functional Consequences and Signal Transduction Induced by IL-3, IL-5, and Nerve Growth Factor in Human Basophils. J Immunol 2001; 167:2282-2291.
- Hemopoietic progenitors: the role of eosoinophil-basophil progenitors in allergic airway inflammation. Expert Rev Clin Immunol 2005; 1:87-101.
- Basophils in airway disease. Curr Allergy Asthma Rep. 2002 Mar;2(2):126?32.
- The Effects of an Anti-CD11a Monoclonal Antibody, Efalizumab, on Allergen-Induced Airway Responses and Airway Inflammation in Atopic Asthmatic Subjects. J Allergy Clin Immunol. 2003; 112:331-338.
Trainees
- Trudy MacLean M.Sc candidate
- Michelle Evans M.Sc candidate
- Aaron Young M.Sc candidate
- Eric Farrell M.Sc candidate
- Lena Saleh M.Sc candidate
- Tara Strinich (Research technician; airway sampling)
- Karen Howie (Research technician; tissue culture)


