Snezana Popovic

, MD, PhD, MSc, FRCPC

Associate Professor
Pathology and Molecular Medicine

Division: Anatomical Pathology

McMaster University
2V17B Health Sciences Centre
905-525-9140 ext. 73646
popovics@hhsc.ca

Education and Professional Standing

• FRCPC, Anatomical Pathology, 2006
• Postdoctoral Research Fellowship, McMaster University, 2000-2002
• PhD (1996) and MSc (1991), University of Belgrade Anatomical Pathology, University of Belgrade, 1994
• MD, University of Belgrade, 1986

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Interests

Research Focus

Dr. Popovic is an Anatomical pathologist with particular interest in bone pathology. The main focus of her research includes morphometric studies on bone metabolism and bone remodeling in metastatic bone disease, primary bone tumours and metabolic bone disease. Investigations also include pathophisiologic changes of bone structure, mass, and bone remodeling at the cell and tissue level, as well as therapeutic modulation of cancer metastasis to bone such as bisphosphonate therapy.

Clinical Focus

Bone Pathology

Academic Interests

Dr. Popovic is involved in the Undergraduate Medical Program and Post-Graduate Residency Training Program.

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Selected Publications

• Vukmirovic-Popovic S, Escott NG, Duivenvoorden WCM: Presence and enzymatic activity of prostate-specific antigen in archival prostate cancer samples. Oncol Rep 20(4):1526-31, 2008.
• Duivenvoorden WCM, Vukmirovic-Popovic S, Kalina M, Seidlitz E, Singh G: Effect of zoledronic acid treatment on doxycycline-induced decrease in tumor burden in a bone metastasis model of human breast cancer. Br J Cancer 96(10):1526-31, 2007.
• Vukmirovic-Popovic S, Seidlitz S, Orr FW, Singh G. Comparative morphometric study on bone remodeling in human specimens and in experimental models of metastatic bone disease. In: Bone metastasis and Molecular Mechanisms: Pathophysiology. Volume 6 Eds: Singh G and Orr FW. Kluwer Academic Publishers, Dordrecht, the Netherlands; 2004.
• Vukmirovic Popovic S, Colterjohn N, Lhotak S, Duivenvoorden WCM, Orr FW, Singh G: Bone alterations in breast carcinoma patients with occult bone metastasis. Bone 31 (4): 529-35, 2002.
• Duivenvoorden CMW, Vukmirovic-Popovic S, Lhotak S, Seidlitz E, Singh G: Doxycycline decreases tumor burden in bone metastasis model of human breast cancer. Cancer Res 62 (6): 1588-91, 2002.
• Lhotak S, Elavathil L, Vukmirovic Popovic S, Duivenvoorden CMW, Tozer GR, Singh G: Immunolocalization of matrix metalloproteinases and their inhibitors in bone metastasis of breast carcinoma. Clin Exp Metastasis 18: 463-470, 2001.