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Major Research Centres
The following major research centres have been recognized for their substantial contribution to research activity at McMaster University and beyond. Members of the Department of Pathology and Molecular Medicine are affiliated with these centres and work in collaboration to conduct research on a wide array of topics. For additional information, click on any centre name.
Antimicrobial Research Centre
The McMaster University Antimicrobial Research Centre (ARC) aims to attack microbial diseases by bringing together a broad spectrum of research interests. Microbial diseases, in particular the increasingly prevalent antibiotic-resistant pathogens, constitute major threats to human health. New diseases have emerged in recent years and old diseases such as tuberculosis, have reappeared in altered forms: many of these are confounding clinicians around the world. The Goal of ARC is to create an environment in which academic and clinical researchers can develop in synergy, allowing the rapid transfer of technology and ideas from the clinic to the lab and back again. It is our belief that this approach is critical to combating the diseases of future generations.
Brain-Body Institute
The Brain-Body Institute is a unique research initiative at St. Joseph's Healthcare. The Institute houses the PET (a 50-cm field of view PET which is capable of mapping the biochemical activity of the brain and lungs simultaneously) and a 3T functional MRI (only the second machine of this sophistication in the world), which provides exquisitely detailed images of the fine structures in the body and reveals the underlying metabolic activity and associated electrophysiological anatomy. The Institute provides a province-wide consortium to optimize neuroimaging research productivity at Ontario Centres by creating a collaborative nexus and by facilitating the development of new tools to translate basic research into clinical applications with strong commercial potential.
Biochemistry and Biomedical Sciences
The Department of Biochemistry and Biomedical Sciences at McMaster University is one of the top centers for life sciences research in North America. The research under way in the laboratories of our faculty members include all of the important areas of academic biomedical research as well as areas of direct relevance to the pharmaceutical industry.
MacGenome: a range of outstanding analytical platforms
McMaster University Genome Sciences is your gateway to state-of-the-art technology platforms for visualization and analysis of DNA, RNA, proteins and small molecules. McMaster University houses outstanding infrastructure that is available to both academic and non-academic users on a fee-for service basis. All facilities are staffed by experienced professionals who will help you plan and execute your projects to achieve your scientific goals. If desired, training on various platforms is available.
Centre for Functional Genomics
The mission of the Centre for Functional Genomics is to develop new technologies and to exploit recent advances in gene expression profiling, bioinformatics and proteomics to discover gene function. This knowledge will be integrated into the investigation of genetic pathways that regulate organismal development and physiology.
McMaster Immunology Research Centre
formerly the Centre for Gene Therapeutics
The mission of the McMaster Immunology Research Centre is to investigate, create and implement approaches utilizing the delivery of genes as therapeutic agents in the treatment of human and animal disease. This entails basic investigations to target gene product involvement, creation of vector systems for appropriate delivery of therapeutic genes and rapid translation of promising medicines to the clinical setting. The Centre is focused on developing novel cures for cancer, inflammatory diseases and infectious diseases using state-of-the-art gene transfer technology coupled with the most recent information derived from the application of genomics.
Infections Research Group
The Infections Research Group (IRG) is a group of infections diseases/microbiology physicians and scientists at McMaster University in Hamilton, Ontario, Canada. Most of our members are based at St. Joseph’s Hospital in Hamilton. We combine clinical insight, technologic expertise, and epidemiologic skills to improve diagnosis and treatment of human infections. Our focus is on respiratory infections, sexually transmitted diseases, and the role of infections in chronic cardiac and respiratory diseases.
Intestinal Disease Research
The Intestinal Disease Research Program (IDRP) conducts bench-to-bedside research in intestinal diseases. This approach allows program to bring new insights from the laboratory to improve the care of patients. Research is primarily conducted under the following themes: Immunophysiology; Enteric Infection-Mucosal Immunology; Gut-Brain Interactions; Pathology of interstitial cells of Cajal. Physiology-Pharmacology; Clinical Research-Therapeutic Trials. The themes represent overlapping areas of research interests, with some IDRP researchers working in more than one theme area. They form the basis of an integrated research program in the area of gut (dys-) function.
