McMaster University

McMaster University

Leslie Berry

Leslie Berry Leslie Berry is a biochemical researcher (part time) who oversees the basic research laboratory of Dr. Anthony Chan in the David Braley Research Institute at the Hamilton General campus. He graduated with a BSc in honours Biochemistry at McMaster in 1977, followed by employment as a research assistant at McMaster in Pathology (1977 – 1987) and then Pediatrics (1987 – present). In 2007, Leslie was awarded an assistant professorship in pediatrics.

His research involves understanding developmental mechanisms in coagulation and fibrinolysis, which has lead to invention of novel treatments. Study of coagulation cascade activation on surfaces of catheters, stents and other blood contacting devices is directed towards solving the main source of thrombosis in children. Work on this problem has resulted in a novel antithrombin-heparin anticoagulant coating that he co-invented. His investigations have also extended into determining the age-related effects of in vivo protein glycosylation on functioning of the Protein C anticoagulant pathway. Recent work to optimize the methods which measure potential of pediatric samples to generate thrombin has evolved into development of a new clinical assay with possible use as a global measure of hemostatic status.

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